Wednesday, May 7, 2014




Growing Cartilage?


Researchers have announced today that they have successfully grown fully functional human cartilage in vitro from human stem cells derived from bone marrow. Their study, which has shown a better, more efficient way to mimic the complexity of tissues, is published in the April 28th issue of Proceedings of the National Academy of Sciences. "We've been able—for the first time—to generate fully functional human cartilage from mesenchymal stem cells by mimicking in vitro the developmental process of mesenchymal condensation," says Gordana Vunjak-Novakovic, who led the study and is the Mikati Foundation Professor of Biomedical Engineering at Columbia Engineering and professor of medical sciences. "This could have clinical impact, as this cartilage can be used to repair a cartilage defect, or in combination with bone in a composite graft grown lab for more complex tissue reconstruction."

This is a very important advancement and will change future medicine though stem cell study, offering ways to overcome the body's limitations. "This is a very exciting time for tissue engineers," says Vunjak-Novakovic. “ We bioengineers are now working with stem cell scientists and clinicians to develop technologies that will make this dream possible.”

NOS: Science is collaborative: many researchers worked to develop this tissue
Role of motivation and curiosity: Dr. Vunjak-Novakovic is motivated to I improve this tissue to use as a
Role of credibility: Mikati Foundation Professor of Biomedical Engineering at Columbia.

1 comment:

  1. Growing cartilage had always sort of intrigued me (primarily because of Grey's Anatomy xD). I was doing some research about cartilage, and its use. I found that currently in the medical field they use shark cartilage to cure/help diseases such as psoriasis, osteoarthritis, and cancer. Growing cartilage could particularly help people with osteoarthritis, which is a cartilage degenerative disease that results in the erosion of joint surfaces and loss of mobility. I found a study that describes in detail about how cartilage tissue engineering could potentially prolong the life of an individual with osteoarthritis.

    Link to the study: http://www.ncbi.nlm.nih.gov/pubmed/16344621

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