Thursday, February 13, 2014

Reducing Disease-Causing Genes by Using RNA Interference

Chemical engineers at MIT are currently working on a new advancement with nanoparticles. These nanoparticles deliver small bits of genetic information to turn off disease causing genes. This new technique is called RNA Interference.

RNA interference is, as of right now, a potential cure for some forms of cancer as well as other various diseases. However, contributing the right amounts of RNA without contributing large amounts of the dangerous side effects is the factor that currently holds this idea back.

The MIT chemical engineers have tested RNA interference with mice. The idea of RNA interference has been around since 1998 and scientist have been working with and experimenting with it ever since. The main goal of the researchers and scientists working on the project is to develop something that can have clinical use in the near future.

Some of the things that have already been tested on include a tumor suppressor gene, and blood clotting protein, and a gene abbreviated as TTR. The test on the TTR was done on primates, not humans.

The chemical engineers are currently working to develop a particle that has improved performance once it is administered. Nanoparticles that target organs different than the liver are also being developed for further testing and use.

Themes of NOS:
  -Science is based on evidence
  -Role of credibility
  -Role of motivation and curiosity

http://www.biologynews.net/archives/2014/02/11/better_rna_interference_inspired_by_nature.html

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